ACTIVATION OF THE NRF2/KEAP1 SIGNALING PATHWAY MEDIATES THE NEUROPROTECTIVE EFFECT OF PERILLYL ALCOHOL AGAINST CEREBRAL HYPOXIC-ISCHEMIC DAMAGE IN NEONATAL RATS

Neonatal hypoxic-ischemic encephalopathy (HIE) is a severe disease with a poor prognosis, whose clinical treatment is still limited to therapeutic hypothermia with limited efficacy.Perillyl alcohol (POH), a natural monoterpene found in various plant essential oils, has shown neuroprotective properties, though its effects on HIE are not well underst

This paper investigates object-based and action-based iconic strategies and combinations of them to refer to everyday objects in the lexicon of an emerging village sign language, namely Central Taurus Sign Language (CTSL) of Turkey.CTSL naturally emerged in the absence 3 IN 1 CEDAR of an accessible language model within the last half century.It pro

The increased prevalence of antibiotic resistance is alarming and has a significant impact on the economies of emerging and underdeveloped nations.The redundancy of antibiotic discovery platforms (ADPs) and injudicious use of conventional antibiotics has severely impacted millions, across the globe.Potent antimicrobials from biological sources have

The genus Minthostachys belonging to the Lamiaceae family, and is an important South #7 MEDIUM BLOND American mint genus used commonly in folk medicine as an aroma in cooking.The phytochemical-rich samples of the aerial parts of Minthostachys diffusa Epling.were tested for pharmacological and health-promoting bioactivities using in vitro chemical a

Investigations regarding means to achieve savings in primary energy use and to decrease anthropogenic CO2 emissions have shown that improved energy efficiency has potential to offer a significant contribution to this cause.Considering energy networks and systems, improvements can be achieved by optimizing the structure of the energy chains and dist